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. Author manuscript; available in PMC: 2017 Aug 18.
Published in final edited form as: Arthritis Rheumatol. 2016 Jun;68(6):1483–1492. doi: 10.1002/art.39572

Figure 5. Significant differences in metagenomic content between SSc patients and healthy controls.

Figure 5

Linear Discriminant Analysis Effect Size (LefSe) multivariate analysis was used to identify significant associations (q<0.1), and Linear Discriminant Analysis (LDA) was used to calculate the effect size for these associations (Supplemental Table 2). Positive LDA score indicates genes and pathways decreased in SSc patients compared with healthy controls. Legend provides color code for cecum and sigmoid data. KEGG= Kyoto Encyclopedia of Genes and Genomes.