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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2017 Jul 7;174(6):595–607. doi: 10.1002/ajmg.b.32565

Table III.

Top Ten Gene Ontology Biological Process Pathways from Main Effect Analyses

GO Pathway ID Pathway Description Observed Gene Count False Discovery Rate p-value
GO.0009893 positive regulation of metabolic process 83 0.000223
GO.0010604 positive regulation of macromolecule metabolic process 68 0.000223
GO.0048518 positive regulation of biological process 108 0.000223
GO.1903707 negative regulation of hematopoiesis 13 0.000223
GO.0019222 regulation of metabolic process 124 0.000393
GO.0045596 negative regulation of cell differentiation 28 0.000393
GO.0048522 positive regulation of cellular process 94 0.00054
GO.0040007 growth 21 0.000644
GO.0045638 negative regulation of myeloid cell differentiation 10 0.000953
GO.0000122 negative regulation of transcription from RNA polymerase II promoter 29 0.00104