Overall |
1.3 |
1.7 |
Age at diagnosis |
≤30 years |
2.5 |
2.5 |
≥60 years |
0.7 |
0.8 |
Subtype (minimum 10 cases) |
Osteosarcoma, not otherwise specified |
1.1 |
1.6 |
Chondroblastic osteosarcoma |
1.7 |
1.9 |
Fibroblastic osteosarcoma |
2.7 |
6.1 |
Telangiectatic osteosarcoma |
2.8 |
2.8 |
Osteosarcoma in Paget’s disease |
0.7 |
1.2 |
Decade of diagnosis |
1970s |
0.9 |
1.0 |
1980s |
0.9 |
1.2 |
1990s |
1.3 |
1.6 |
2000s |
1.5 |
2.0 |
Extent of disease |
Confined |
4.3 |
N/A |
Locally invasive |
1.9 |
2.5 |
Metastatic |
0.7 |
0.8 |
Treatment modality |
Surgery+Radiation therapy |
1.7 |
2.2 |
Surgery only |
3.6 |
3.4 |
Radiation only |
0.7 |
0.8 |
No therapy |
0.8 |
1.0 |
|
Percent survival |
|
At 2 years |
27 |
36 |
At 5 years |
18 |
27 |
At 10 years |
14 |
22 |
|
Ewing sarcoma (n=736) |
|
Median survival (years) |
Overall survival |
Disease-specific survival |
|
Overall |
3.9 |
4.3 |
Decade of diagnosis |
1970s |
1.7 |
1.7 |
1980s |
2.5 |
2.7 |
1990s |
3.6 |
4.0 |
2000s |
5.9 |
6.3 |
Extent of disease |
Confined |
N/A |
N/A |
Locally invasive |
8.9 |
N/A |
Metastatic |
1.9 |
2.0 |
Treatment modality |
Surgery+Radiation therapy |
11.6 |
16.1 |
Surgery only |
6.7 |
N/A |
Radiation only |
2.8 |
3.0 |
No therapy |
2.0 |
2.2 |
Percent survival |
At 2 years |
55 |
57 |
At 5 years |
44 |
45 |
At 10 years |
37 |
40 |