Table IV.
Differentially expressed genes in the IVM, IVM-anti and in vivo groups.
| A, IVM group vs. in vivo group | |||||
|---|---|---|---|---|---|
| Gene symbol | GenBank accession | Regulation direction | FDR | P-value | Biological processes |
| MAT2A | NM_005911 | Up | 0.99997 | 0.03405 | S-adenosylmethionine synthetase |
| COMT | NM_000754 | Up | 0.70388 | 0.00733 | Catechol-O-methyltransferase |
| ZNF335 | NM_022095 | Up | 0.96627 | 0.01522 | Methylation |
| PER1 | NM_002616 | Up | 0.99997 | 0.01977 | Cation channel sperm-associated protein 1 |
| FOXO3 | NM_001455 | Up | 0.99997 | 0.02969 | Transcription factors |
| STK4 | NM_006282 | Down | 0.97854 | 0.01614 | Phosphorylating |
| NPHP4 | NM_015102 | Down | 0.99997 | 0.03147 | Chromosome and associated proteins |
| B, IVM-anti group vs. IVM group | |||||
| Gene symbol | GenBank accession | Regulation direction | FDR | P-value | Biological processes |
| CCNE1 | NM_001238 | Up | 0.47303 | 0.01166 | G1/S-specific cyclin E1 |
| CCNG1 | NM_004060 | Up | 0.30861 | 0.00296 | Cyclin G1 |
| MAT2A | NM_005911 | Down | 0.58916 | 0.03081 | S-adenosylmethionine synthetase |
| IL4I1 | NM_152899 | Down | 0.60742 | 0.04633 | L-amino-acid oxidase |
| ATP8 | AK128101 | Down | 0.44454 | 0.00934 | Mitochondrial biogenesis |
| C, IVM-anti group vs. in vivo group | |||||
| Gene symbol | GenBank accession | Regulation direction | FDR | P-value | Biological processes |
| DUSP4 | NM_001394 | Up | 0.10966 | 0.00199 | Dual specificity MAP kinase phosphatase |
| LRG1 | NM_052972 | Up | 0.12045 | 0.00249 | DNA repair and recombination proteins |
| ATP5J | NM_001003703 | Down | 0.36829 | 0.03604 | ATP synthase |
| COX6B | NM_144613 | Down | 0.13547 | 0.00334 | Cytochrome c oxidase subunit 6b |
FDR was estimated to evaluate the probability of false positive associations. FDR, false discovery rate; IVM, in vitro maturation; MAT2A, methionine adenosyltransferase 2A; COMT, catechol-O-methyltransferase; ZNF335, zinc finger protein 335; PER1, period circadian clock 1; FOXO3, forkhead box O3; STK4, serine/threonine kinase 4; NPHP4, nephrocystin 4; CCNE1, cyclin E1; CCNG1, cyclin G1; IL4I1, interleukin 4 induced 1; ATP8, ATP synthase F0 subunit 8; DUSP4, dual specificity phosphatase 4; LRG1, leucine rich α-2-glycoprotein 1; ATP5 J, ATP synthase H+ transporting, mitochondrial Fo complex subunit F6; COX6B, cytochrome c oxidase subunit 6B1.