Table VI.
Significantly enriched Gene Ontology and pathways of blastocysts in the IVM-anti group vs. in vivo group.
| GO/pathway ID | Regulation direction | Count | Description | Gene symbol |
|---|---|---|---|---|
| GO:0010563 | Up | 29 | Negative regulation of phosphorus metabolic process | DUSP4, CAV1, MEN1, NTRK3, DNAJC10, PID1, MICAL1, ZBED3, PPAP2B |
| GO:0030511 | Up | 29 | Positive regulation of transforming growth factor β receptor signaling pathway | LRG1, FLCN, MEN1, THBS1, MYOCD |
| hsa04115 | Up | 7 | p53 signaling pathway | CCNE1, CCNG1, DDB2, PPM1D, SHISA5, STEAP3, THBS1 |
| hsa00190 | Down | 8 | Oxidative phosphorylation | ATP5J, ATP8, COX6B2, ND1, ND2, ND3, NDUFA6, SDHC |
| hsa05012 | Down | 2 | Parkinson's disease | ATP5J, ATP8, COX6B2, ND1, ND2, ND3, NDUFA6, SDHC, UBA7 |
Pathway IDs were produced from KEGG analysis. Count indicates the number of differentially expressed genes associated with the listed GO/pathway ID. IVM, in vitro maturation; GO, gene ontology.