Figure 1.

Tremella fuciformis polysaccharide (TFPS) alleviates hydrogen peroxide-triggered human skin fibroblast injury. (A) Human skin fibroblasts were cultured in the presence of TFPS (0, 10, 20, 50, 100, 200, and 300 µg/ml), for 24 h, and cell viability was measured by MTT assay (n=3). (B) Human skin fibroblasts were cultured in the presence of H₂O₂ (100, 200, 300, 400, 500, and 600 µM) for 24 h, and cell viability was analyzed by MTT assay (n=3). (C) Human skin fibroblasts were pre-treated with TFPS (50, 100, 200, and 300 µg/ml) for 1 h, and then 300 µM H₂O₂ was applied for 24 h. Cell viability was determined by MTT assay (n=4) (*P<0.05 and ***P<0.001 vs. the control group; ^#P<0.05 vs. the 300 µM H₂O₂ group).