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. 2017 Jun 14;16(2):1957–1963. doi: 10.3892/mmr.2017.6779

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Copyright: © Guo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — BMP-7 promotes activation of the BMP-7/Smad1/5/8 signaling pathway. (A) The protein expression levels of BMP-7, p-Smad1/5/8 and Smad1/5/8 were detected by western blot analysis. β-actin was used as a loading control. Results of densitometric analysis for (B) BMP-7 and (C) p-Smad1/5/8/Smad1/5/8 protein expression. The results are presented as the mean + standard deviation (n=6), and are representative of three independent experiments. *P<0.05, **P<0.01 and ***P<0.001 vs. control group; ^#P<0.05 and ^##P<0.01 vs. untreated thermal injury group. BMP-7, bone morphogenetic protein-7; p-, phosphorylated-.