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. 2016 May 12;11(11):1393–1406. doi: 10.2217/nnm-2016-0006

Figure 1. . Liposome characterization: pharmacokinetics and biodistribution.

Figure 1. 

(A) Representative transmission electrical microscopy of Lipo-SP; (B) diameter distribution of Lipo-SP; (C) plasma pharmacokinetic analysis of Lipo-SP and Free-SP in mice; (D) SP tissue distribution in bleomycin-treated mice 2 h following oral administration. *p < 0.05 (n = 5–7); and (E–H) dynamic profiles of SP organ distribution following oral administration.

Free-SP: Free spironolactone; Lipo-SP: Liposome-entrapped spironolactone; SP: Spironolactone.