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MSEA was implemented to evaluate metabolic pathway enrichment among the tuberculous, transudative and malignant pleural effusion groups. MSEA indicated that the alanine, glutamate, methionine, choline, threonine, serine, betaine, lipid, starch, sucrose and pyruvate metabolism, and citrate cycle, glycolysis, gluconeogenesis and phospholipid biosynthesis are significantly associated with these diseases. MSEA, metabolite set enrichment analysis.
