Table II.

Functional annotation of hsa-miR-326 targets.

A, Biological processes
Term	Function	Count	P-value
GO:0048666	Neuron development	20	1.10×10-4
GO:0030182	Neuron differentiation	22	4.20×10−4
GO:0042127	Regulation of cell proliferation	32	6.13×10-4
GO:0045197	Establishment or maintenance of epithelial cell apical/basal polarity	4	7.15×10−4
GO:0044057	Regulation of system process	17	9.04×10-4
B, Cellular components
Term	Function	Count	P-value
GO:0044459	Plasma membrane part	72	3.26×10−5
GO:0005886	Plasma membrane	107	7.61×10-5
GO:0005911	Cell-cell junction	12	1.82×10−3
GO:0031965	Nuclear membrane	7	3.72×10-3
GO:0030054	Cell junction	21	4.78×10−3
C, Molecular function
Term	Function	Count	P-value
GO:0019904	Protein domain specific binding	18	1.00×10-3
GO:0003707	Steroid hormone receptor activity	6	4.20×10−3
GO:0004879	Ligand-dependent nuclear receptor activity	6	8.61×10-3
GO:0016247	Channel regulator activity	6	9.24×10−3
GO:0005249	Voltage-gated potassium channel activity	7	2.24×10-2
D, KEGG pathways
Term	Function	Count	P-value
hsa05200	Pathways in cancer	19	5.37×10−4
hsa04360	Axon guidance	10	3.02×10-3
hsa04720	Long-term potentiation	7	4.86×10−3
hsa05211	Renal cell carcinoma	7	5.60×10-3
hsa05223	Non-small cell lung cancer	6	8.18×10−3
E, REACTOME pathways
Term	Function	Count	P-value
REACT_9417	Signaling by epidermal growth factor receptor	6	4.27×10-3
REACT_11061	Signaling by nerve growth factor	11	6.89×10−3

GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.