Table 2.
The detection of resistance genes of Helicobacter pylori in biopsy and corresponding isolates by direct high-throughput multiple genetic detection system.
Antibiotics | Gene | Isolates | Biopsy
|
||
---|---|---|---|---|---|
WT | MT | Mixed | |||
CLA | 23S rRNA | 2143_A | 27 | 1 | 2 |
2143_G | 0 | 7 | 3 | ||
| |||||
MTZ | rdxA | 148_C | 37 | 0 | 0 |
148_T | 1 | 1 | 1 | ||
| |||||
AMX | pbp1A | 1777_A | 25 | 1 | 7 |
1777_G | 1 | 5 | 1 | ||
| |||||
LEV | gyrA | 261_C/T | 30 | 0 | 2 |
261_G/A | 0 | 6 | 2 |
The performance parameters have been calculated using formulas described in the ‘Materials & methods’ section. AMX: Amoxicillin; CLA: Clarithromycin; LEV: Levofloxacin; MT: Mutant; MTZ: Metronidazole; WT: Wild-type.