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. 2017 Jun 22;38(2):785–798. doi: 10.3892/or.2017.5742

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Copyright: © Lang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — ncU87-Exo and shU87-Exo decrease HUVEC apoptosis induced by hypoxia in vitro. Both ncU87-Exo and shU87-Exo decreased apoptosis of HUVECs induced by hypoxia, and ncU87-Exo exhibited more efficient anti-apoptosis. (A) Representative FCM images of PI and Annexin V-FITC double-stained HUVEC apoptosis. (B) The bar chart of PI and Annexin V-FITC double-stained HUVEC apoptosis. (*P<0.01, hypoxia (−) group vs. hypoxia (+) control medium, ncU87-Exo and shU87-Exo group; ^#P<0.05, hypoxia (+) ncU87-Exo and shU87-Exo group vs. hypoxia (+) control medium; ^&P<0.05, hypoxia (+) ncU87-Exo group vs. hypoxia (+) shU87-Exo group). HUVECs, human umbilical vein endothelial cells.