Table II.
MFI in T98G, U2OS and SaOS2 cells in the presence of inhibitors +/− X-ray.
| Cell line | Reagent | MFI (−IR) | MFI (10 Gy) | Fold increase of IR-induced MFI |
|---|---|---|---|---|
| T98G | DMSO | 3.65 | 3.79 | 1.02 |
| Vorinostat | 18.94 | 32.13 | 1.76 | |
| TSA | 67.66 | 108.0 | 1.60 | |
| Chaetocin | 8.59 | 13.13 | 1.44 | |
| Bix-01294 | 4.37 | 5.72 | 1.38 | |
| 5-Aza-cytidine | 4.76 | 4.54 | 0.99 | |
| Zebularine | 5.48 | 5.94 | 1.06 | |
| NU9056 | 4.92 | 4.95 | 1.03 | |
| U2OS | DMSO | 84.70 | 105.50 | 1.25 |
| Vorinostat | 190.89 | 251.0 | 1.31 | |
| SaOS2 | DMSO | 168.91 | 207.61 | 1.23 |
| Vorinostat | 389.26 | 493.79 | 1.27 |
MFI, mean fluorescence intensity; IR, ionizing radiation; DMSO, dimethyl sulfoxide; TSA, trichostatin A.