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. 2017 Jun 19;16(2):1793–1800. doi: 10.3892/mmr.2017.6802

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — PIO inhibits mast cells granule formation. Bone marrow cells were cultured in IL-3 and SCF with PIO at the indicated concentrations for 4 weeks. (A) Cells were stained with toluidine blue and pictures depicted are at a magnification of ×400. (B) Degranulation of BMMCs was detected by measuring the activity of β-hexosaminidase. The data is representative of three independent experiments. *P<0.05 vs. vehicle, **P<0.01 vs. vehicle. PIO, pioglitazone; SCF, stem cell factor; BMMCs, bone marrow-derived mast cells.