Table III.

Signaling pathways significantly represented by glucose-6-phosphate dehydrogenase-associated genes.

Pathway ID	Pathway name	Genes	Count	Enrichment P-value
4060	Cytokine-cytokine receptor interaction	EGF, IL1B, CSF3, TNF, IFNA1, PDGFRB, EGFR, IL6, IL2, IL10	10	5.28×10−3a
4010	MAPK signaling pathway	EGF, IL1B, ATF4, TP53, TNF, PDGFRB, EGFR, HSPB1, DUSP1, IKBKG	10	6.51×10−3a
4510	Focal adhesion	CCND1, EGF, VASP, PTEN, PDGFRB, BCL2, EGFR, PPP1R12A, IGF1	9	2.75×10−3a
4630	Jak-STAT signaling pathway	CCND1, CSF3, IFNA1, STAT3, IL6, IL2, IL10	7	8.11×10−3a
4910	Insulin signaling pathway	INSR, HK1, INS, FBP2, GCK, FASN	6	1.67×10−2
4020	Calcium signaling pathway	NOS1, PLCG1, PDGFRB, EGFR, NOS3, GNAS	6	4.95×10−2
4115	p53 signaling pathway	CCND1, TP53, PTEN, IGF1, CDKN2A	5	3.30×10−3a
4730	Long-term depression	NOS1, PRKG1, NOS3, IGF1, GNAS	5	3.98×10−3a
4210	Apoptosis	IL1B, TP53, TNF, BCL2, IKBKG	5	9.85×10−3a
4540	Gap junction	EGF, PDGFRB, EGFR, PRKG1, GNAS	5	1.13×10−3
4620	Toll-like receptor signaling pathway	IL1B, TNF, IFNA1, IL6, IKBKG	5	1.72×10−2
4660	T cell receptor signaling pathway	TNF, PLCG1, IL2, IL10, IKBKG	5	2.23×10−2
4920	Adipocytokine signaling pathway	TNF, STAT3, SLC2A1, IKBKG	4	1.75×10−2
4370	VEGF signaling pathway	PLCG1, HSPB1, PTGS2, NOS3	4	2.54×10−2
4640	Hematopoietic cell lineage	IL1B, CSF3, TNF, IL6	4	4.07×10−2
4612	Antigen processing and presentation	IFNA1, CREB1, HSPA5, HSP90AA1	4	4.22×10−2

^aP<0.01.