Table IV.
Metabolic pathways significantly represented by glucose-6-phosphate dehydrogenase-associated genes.
| Metabolic pathway | Genes | Count | Enrichment P-value |
|---|---|---|---|
| Pentose phosphate pathway | TKT, FBP2, GPI, PGD | 4 | 5.42×10−4a |
| Fructose and mannose metabolism | AKR1B1, SORD, HK1, FBP2 | 4 | 1.37×10−3a |
| Glycerolipid metabolism | AKR1B1, GLA, LPL, AKR1A1 | 4 | 4.72×10−3a |
| Starch and sucrose metabolism | UGT1A1, HK1, GCK, GPI | 4 | 7.32×10−3a |
| Nitrogen metabolism | CA1, CA2, CA3 | 3 | 5.22×10−3a |
| Galactose metabolism | AKR1B1, HK1, GLA | 3 | 5.87×10−3a |
| Glutathione metabolism | GSS, GSR, PGD | 3 | 3.83×10−2 |
| Drug metabolism-other enzymes | UGT1A1, HPRT1, XDH | 3 | 4.03×10−2 |
| Amino sugar and nucleotide sugar metabolism | HK1, GCK, CYB5R3 | 3 | 2.60×10−2 |
a
P<0.01.