Table V.

Diseases significantly represented by glucose-6-phosphate dehydrogenase-associated genes.

Disease	Genes	Count	Enrichment P-value
Prostate cancer	CCND1, EGF, AR, ATF4, TP53, PTEN, PDGFRB, BCL2, EGFR, INS, CREB1, HSP90AA1, IGF1, IKBKG	14	2.81×10−11a
Glioma	CCND1, EGF, TP53, PTEN, PLCG1, PDGFRB, EGFR, IGF1, CDKN2A	9	3.79×10−7a
Melanoma	CCND1, EGF, TP53, PTEN, PDGFRB, EGFR, IGF1, CDKN2A	8	8.66×10−6a
Small cell lung cancer	CCND1, NOS1, TP53, PTEN, BCL2, PTGS2, NOS3, IKBKG	8	3.61×10−5a
Amyotrophic lateral sclerosis	CAT, NOS1, TP53, TNF, BCL2, SOD1, NOS3	7	1.46×10−5a
Pancreatic cancer	CCND1, EGF, TP53, EGFR, STAT3, CDKN2A, IKBKG	7	8.63×10−5a
Non-small cell lung cancer	CCND1, EGF, TP53, PLCG1, EGFR, CDKN2A	6	1.35×10−4a
Alzheimer's disease	IL1B, NOS1, TNF, LPL, NOS3, ATP5A1	6	3.72×10−2
Bladder cancer	CCND1, EGF, TP53, EGFR, CDKN2A	5	3.65×10−4a
Type II diabetes mellitus	TNF, INSR, HK1, INS, GCK	5	6.20×10−4a
Endometrial cancer	CCND1, EGF, TP53, PTEN, EGFR	5	9.91×10−4a
Colorectal cancer	CCND1, TP53, PDGFRB, BCL2, EGFR	5	8.13×10−3a
Type I diabetes mellitus	IL1B, TNF, INS, IL2	4	3.69×10−3a
Chronic myeloid leukemia	CCND1, TP53, CDKN2A, IKBKG	4	2.54×10−2
Graft-vs.-host disease	IL1B, TNF, IL6, IL2	4	3.10×10−3a
Autoimmune thyroid disease	IFNA1, IL2, IL10	3	4.23×10−2

^aP<0.01.