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. 2017 Jun 8;16(2):1347–1352. doi: 10.3892/mmr.2017.6729

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Treatment with SK combined with ADM for 48 h increases osteosarcoma apoptosis. In the U2OS and MG63 cells, apoptosis was significantly higher in the ADM group, compared with the SK group. Apoptosis in the SK+ADM group was higher, compared with that in the SK group. **P<0.01. SK, shikonin; ADM, Adriamycin; Ctrol, control.