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. 2017 Jun 23;14(7):668–674. doi: 10.7150/ijms.17865

Table 2.

Summary of the bivariate indices of diagnostic accuracy of low SI in the HBP.

REFERENCE N TP TN FP FN Sen Spe LR+ LR-
Bieze M 52 23 27 1 1 0.958 0.964 20.833 0.043
Grazioli L 111 40 62 6 3 0.930 0.912 10.543 0.077
Mohazjer K 40 6 34 0 0 1.000 1.000 65.000 0.072
Purysko AS 47 12 32 3 0 1.000 0.914 9.890 0.043
Grieser C 115 62 44 0 9 0.873 1.000 78.125 0.133
Portilha 32 8 23 1 0 1.000 0.958 15.741 0.059
POOLED RESULT 0.921 0.953 13.827 0.103
95% CI (0.868-0.957) (0.917-0.976) (7.811-24.479) (0.064-0.167)
P* 0.237 0.059 0.366 0.691
I2 %§ 26.3% 53.0% 7.8% 0.0%

*p value use the Cochran-Q method to test the heterogeneity of the pooled data. Values <0.05 indicate substantial heterogeneity. §I2 is the Higgin′s index for heterogeneity and values greater than 50 % indicate substantial heterogeneity.

Abbreviations: TP=true positive; TN=true negative; FP=false positive; FN=false negative; Spe=specificity; Sen=sensitivity; LR+=positive likelihood ratio; LR-=negative likelihood ratio.