Table 2.
Neurometabolites and spectral quality indices 1
| Saline | Ketamine | t/F | p value | |
|---|---|---|---|---|
| Neurometabolite measurements | ||||
| Glx | 0.62 (0.13) | 0.69 (0.08) | 3.756 | 0.042 |
| NAA | 1.35 (0.10) | 1.38 (0.16) | 0.346 | 0.57 |
| Cho | 0.94 (0.12) | 0.96 (0.16) | 0.151 | 0.70 |
| Spectral quality indices | ||||
| Glx CRLB | 0.09 (0.02) | 0.10 (0.02) | -2.182 | 0.05 |
| NAA CRLB | 0.04 (0.01) | 0.04 (0.01) | -1.799 | 0.09 |
| Cho CRLB | 0.03 (0.01) | 0.03 (0.01) | -1.713 | 0.11 |
| FWHM | 7.42 (1.32) | 7.63 (1.46) | -0.694 | 0.50 |
| SNR | 12.57 (1.76) | 11.89 (1.85) | 1.260 | 0.23 |
| Voxel tissue fraction | ||||
| grey matter (%) | 63.67 (4.64) | 63.11 (6.00) | 0.527 | 0.61 |
| white matter (%) | 33.64 (4.81) | 34.42 (6.45) | -0.701 | 0.50 |
| cerebrospinal fluid (%) | 2.68 (0.14) | 2.47 (0.16) | 1.009 | 0.33 |
Abbreviations: Cho Choline; CRLB, Cramer Rao Lower Bounds; FWHM Full width at half maximum; Glx glutamate+glutamine; NAA N-acetyl-aspartate; SNR Signal to noise ratio
1
Mean (SD) unless indicated otherwise, n= 15
2
one-sided F test