Table 1.

Sensitivity, positive predictive value and AFROC-AUC for detection of hepatic metastases

Reader	Technique	Sensitivity			PPV			AFROC-AUC
1	Gadoxetic acid	104/145	72 %	(62–84 %)	104/106	98 %	(95–100 %)	0.86	(0.79–0.92)
	Gadoxetic acid + gadofosveset	130/145	90 %	(83–97 %)	130/137	95 %	(91–99 %)	0.92	(0.87–0.97)
	P value	P=0.0038			P = 0.051			P=0.0020
2	Gadoxetic acid	103/145	71 %	(61–82 %)	103/114	90 %	(79–100 %)	0.87	(0.81–0.93)
	Gadoxetic acid + gadofosveset	124/145	86 %	(78–94 %)	124/141	88 %	(77–100 %)	0.93	(0.88–0.97)
	P value	P=0.0038			P=0.071			P =0.0017

Numbers indicate lesions that were used for calculating the percentages with 95 % confidence intervals (in parenthesis). Sensitivities and specificities are calculated using each marked lesion as readers’ judgment for a positive finding. P values < 0.05 indicate statistical significant differences, significant values are in bold

PPV positive predictive value, AFROC alternative free-response receiver-operating characteristic, AUC area under the curve