Figure 1.

VSV-p14 Induces Syncytium Formation and Enhances Virus Dissemination and Yield

(A) Schematic of recombinant VSV containing gene insertions encoding either GFP or the p14 FAST protein. (B) Vero cells were mock-infected or infected with the indicated recombinant viruses at an MOI of 0.1 and Giemsa-stained at 24 hpi to detect syncytium formation. (C) As in (B), using the supernatant from infected cultures to determine the virus yield by plaque assay at the indicated times post-infection. Results are mean ± SEM from duplicate experiments. *p < 0.05 compared with VSV-GFP.