Table 1. Summary of significantly different metabolic processes.

These specific metabolisms were significantly over represented and found within the pathways driving differences between treatments in the metabolism CDA.

Organism over represented		Broad metabolic processes	Gene pathways	ETA/P value
Zoanthid		Regulation and cell signaling	Phd-Doc, YdcE-YdcD toxin-antitoxin	η2 = 0.662p = 0.012
Zoanthid		Nucleoside and nucleotides	Purine utilization	η2 = 0.650p = 0.014
Zoanthid		Stress response	Bacterial hemoglobins	η2 = 0.621p = 0.021
Zoanthid		Stress response	Universal stress protein family	η2 = 0.650p = 0.014
Zoanthid		Respiration	Respiratory dehydrogenases	η2 = 0.682p = 0.008
Zoanthid		Respiration	Terminal cytochrome C oxidases	η2 = 0.553p = 0.048
Zoanthid		Virulence disease and defense	Adhesions in staphylococcus	η2 = 0.658p = 0.013
Zoanthid		Virulence disease and defense	Arsenic resistance	η2 = 0.559p = 0.045
Zoanthid		Phosphorus metabolism	P uptake	η2 = 0.750p = 0.002
Zoanthid		Phosphorus metabolism	Phosphate-binding DING proteins	η2 = 0.713p = 0.005
Zoanthid		RNA metabolism	Group II intron-associated genes	η2 = 0.598p = 0.029
Zoanthid		RNA metabolism	Polyadenylation specificity factors	η2 = 0.697p = 0.006
Zoanthid		RNA metabolism	RNA polymerase III initiation factor	η2 = 0.562p = 0.044
Zoanthid		DNA metabolism pathways	2-phosphoglycolate salvage	η2 = 0.670p = 0.011
Turf algae	Zoanthid	Membrane transport	Fap amyloid fiber secretion	η2 = 0.606p < 0.001
Turf algae	Zoanthid	Membrane transport	General secretion	η2 = 0.667p = 0.011
Turf algae		Membrane transport	NhaA, NhaD and Sodium-dependent phosphate transporters	η2 = 0.605p = 0.026
Turf algae		Membrane transport	Fructose and mannose inducible PTS	η2 = 0.578p = 0.036
Turf algae		Membrane transport	Galactose-inducible PTS	η2 = 0.623p = 0.021
Turf algae		Membrane transport	Sucrose-specific PTS	η2 = 0.611p = 0.024
Turf algae		Membrane transport	Phosphoglycerate transport	η2 = 0.835p < 0.001
Turf algae		Membrane transport	Type III secretion	η2 = 0.628p = 0.019
Turf algae		Nucleoside and nucleotides	Pyrimidine conversions	η2 = 0.559p = 0.045
Turf algae		Respiration	Tetrathionate respiration	η2 = 0.635p = 0.018
Turf algae	Fleshy macroalgae	Respiration	Methanogenesis strays	η2 = 0.800p = 0.026
Fleshy macroalgae		Respiration	Carbon monoxide dehydrogenase maturation factors	η2 = 0.557p = 0.046
Water Column		Cell division and cell cycle	YgjD and YeaZ	η2 = 0.702p = 0.006
Water Column		RNA metabolism	tRNA modification	η2 = 0.582p = 0.035
Coral	Water Column	RNA metabolism	Mnm5U34 biosynthesis	η2 = 0.566p = 0.041
Coral	Water Column	Nucleoside and nucleotides	De Novo purine biosynthesis	η2 = 0.648p = 0.015
Coral		Virulence disease and defense	Methicillin resistance	η2 = 0.635p = 0.017
Coral		DNA metabolism pathways	DNA repair base excision	η2 = 0.589p = 0.032
Coral		Cofactors, vitamins, prosthetic groups, and pigments	Pterin metabolism 3	η2 = 0.626p = 0.020
Coral		Vitamins, prosthetic groups, and pigments	Riboflavin to FAD	η2 = 0.587p = 0.033
Coral		Vitamins, prosthetic groups, and pigments	YgfZ	η2 = 0.638p = 0.017