Skip to main content
. 2017 Jul 19;14(9):840–852. doi: 10.7150/ijms.19268

Figure 2.

Figure 2

Effect of Niclosamide on RANK-induced osteoclast differentiation of RAW264.7 and on MCSF- and RANKL induced osteoclast differentiation of BMM. (A). RAW 264.7 cells were treated with or differentiation concentration of Niclosamide in the presence of RANKL(100ng/ml) for 5 days. (B) BMM treated with or without niclosamide in present MCSF(30ng/ml) and RANKL(100ng/ml) for 5days. After the culture, the cells were fixed and stained by TRAP. The TRAP-positive multinucleated cells containing more than 5 nuclei were considered as mature osteoclast. The data represent mean ± SD (n=3). *P<0.05, compared with the 0 uM (DMSO) group.