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Effects of niclosamide on resorption pit formation. BMMs were cultured on bone slices with differentiation concentrations of niclosamide in the presence of MCSF(30ng/ml) and RANKL(100ng/ml) for 5days. After incubation, resorbed lacunae on the bone slices were visualized using light microscopy. The percentages of resorbed area relative to control group were calculated using ImageJ software. *, p < 0.05 and **, p < 0.01 compared with RANKL-treated group.
