Table 5.
Comparison of inflammatory markers hsCRP and monocyte subsets (counting and phenotype) between groups with and without central obesity (n=57)
| No CO | CO | |||||
|---|---|---|---|---|---|---|
| F | df | Mean ± SEM/ * | Mean ± SEM/ * | p | ||
| hsCRP* (mg/L) | - | - | 0.757 (0.469-2.090) | 1.530 (0.764-3.560) | 0.160 | |
| Monocytes subsets | ||||||
| cells/μL | CD16+ | 0.055 | 1, 54 | 53±18 | 49±6 | 0.816 |
| CD16- | 1.747 | 1, 54 | 431±38 | 375±21 | 0.192 | |
| Ratio number | 0.404 | 1, 54 | 0.12±0.03 | 0.13±0.01 | 0.528 | |
| FSC | CD16+ | 0.227 | 1, 54 | 547±17 | 556±10 | 0.636 |
| CD16- | 0.080 | 1, 54 | 549±17 | 554±10 | 0.778 | |
| Ratio FSC | 0.833 | 1, 54 | 1±0.01 | 1±0.01 | 0.365 | |
| SSC | CD16+ | 3.998 | 1, 54 | 431±16 | 400±8 | 0.051 |
| CD16- | 0.371 | 1, 54 | 485±13 | 477±7 | 0.545 | |
| Ratio SSC | 9.684 | 1, 54 | 0.89±0.01 | 0.84±0.01 | 0.003 | |
| CD14 | CD16+ | 0.285 | 1, 50 | 968±167 | 867±93 | 0.596 |
| CD16- | 1.292 | 1, 53 | 1865±326 | 2423±264 | 0.261 | |
| Ratio CD14 | 8.974 | 1, 54 | 0.50±0.05 | 0.36±0.02 | 0.004 | |
| CD36 | CD16+ | 0.108 | 1, 54 | 327±52 | 313±18 | 0.743 |
| CD16- | 2.330 | 1, 54 | 670±68 | 765±28 | 0.133 | |
| Ratio CD36 | 3.826 | 1, 54 | 0.50±0.04 | 0.42±0.02 | 0.056 | |
| CD11b | CD16+ | 0.000 | 1, 24 | 80±30 | 81±18 | 0.996 |
| CD16- | 0.621 | 1, 24 | 125±48 | 241±78 | 0.438 | |
| Ratio CD11b | 2.311 | 1, 24 | 0.69±0.07 | 0.51±0.06 | 0.141 | |
CO, central obesity; FSC, forward scatter; SSC, side scatter; Values of CD14, CD36 and CD11b expressed as fluorescence arbitrary units (AU); Ratio SSC, ratio between side scatter (SSC) of CD16+monocytes and SSC of CD16- monocytes in each individual; Ratio CD1, ratio between the expression of CD14 on CD16+monocytes and the expression of CD14 on CD16- monocytes in each individual; Ratio CD11b, ratio between the expression of CD11b on CD16+monocytes and the expression of CD11b on CD16- monocytes in each individual; Data are presented as mean ± standard error of the mean (SEM); F Snedcor's distribution; df degrees of freedom; p level of significance. * Data presented as median (25th-75th percentiles) and Mann-Whitney test used for comparison between the two groups.