Table 1.
Clinical and laboratory characteristics of patients with heart failure with reduced and preserved left ventricular ejection fraction
| Variables N (%) |
HFr-EF (n=32) |
HFp-EF (n=43) |
P value |
|---|---|---|---|
| Age, years | 62.5 ± 10.3 | 62.8 ± 11.5 | 0.718 |
| Male gender | 26 (81.3) | 28 (65.1) | 0.003 |
| Body mass index, kg/m2 | 26.6 ± 4.4 | 29.4 ± 5.3 | 0.03 |
| LVEF, % | 34.9 ± 3.9 | 60.4 ± 8.5 | <0.001 |
| Cardiovascular risk factors | |||
| Current smoking | 14 (43.8) | 16 (37.2) | 0.267 |
| Dyslipidemia | 15 (46.9) | 23(53.5) | 0.317 |
| Hypertension | 17 (53.1) | 25 (58.1) | 0.296 |
| Diabetes mellitus | 10 (31.3) | 16 (37.2) | 0.277 |
| Obesity | 14 (43.8) | 21 (48.8) | 0.127 |
| Coronary artery disease | 19 (59.4) | 17 (39.5) | 0.04 |
| Multivessel coronary disease | 22 (68.8) | 30 (69.8) | 0.431 |
| Valve heart disease | 15 (46.9) | 28 (65.1) | 0.03 |
| Cerebrovascular disease | 3 (9.4) | 3 (7) | 0.442 |
| Medications | |||
| Aspirin | 17 (53.1) | 24 (55.8) | 0.766 |
| Statin | 14 (43.8) | 22 (51.2) | 0.104 |
| ACEI/ARB | 19 (59.4) | 25 (58.1) | 0.425 |
| Beta-blocker | 21 (65.6) | 31 (72.1) | 0.370 |
| Biochemical data | |||
| Glucose, mg/dL | 129.8 ± 57.7 | 122.1 ± 43.7 | 0.349 |
| HbA1c, % | 6.6 ± 1.3 | 6.2 ± 1.3 | 0.721 |
| Total cholesterol, mg/dL | 160± 36 | 163± 42 | 0.395 |
| LDL cholesterol, mg/dL | 97± 39 | 98± 33 | 0.381 |
| HDL cholesterol, mg/dL | 40± 8.5 | 39 ± 14 | 0.320 |
| Triglycerides, mg/dL | 161± 53 | 144± 61 | 0.197 |
| Creatinine, mg/dL | 1.3± 0.8 | 1 ± 0.4 | 0.711 |
| Uric acid, mg/dL | 6.7± 3.6 | 5.6± 1.9 | 0.07 |
| GOT, IU/L | 28.9± 11.9 | 35.3 ± 37 | 0.112 |
| GPT, IU/L | 33.9± 18.9 | 36.9± 29.1 | 0.426 |
| GGT, IU/L | 61.6± 44.8 | 52.1± 57.6 | 0.479 |
| CRP, mg/dL | 27.1± 46.6 | 17± 32.9 | 0.222 |
| Calcium, mg/dL | 8.5 ± 0.7 | 8.5± 0.8 | 0.858 |
| Potassium, mmol/L | 4.2± 0.7 | 4.3± 0.4 | 0.855 |
| Sodium, mmol/L | 136± 4.4 | 138± 3.5 | 0.342 |
Values are shown as mean ± standard deviation and frequencies (percentages).
Values were considered to be statistically significant when P<0.05.
ACEI: Angiotensin Converting Enzyme Inhibitor; ARB: Antiotensin II Receptro Blocker; CRP: C-Reactive Protein; GGT: Gamma-Glutamyl Transferase; GOT: Glutamic-Oxolacetic Transaminase; GPT: Glutamate-Piruvate Transaminase; Hb1ac: glycated hemoglobin; HDL: High-Density Lipoprotein; HFp-EF: heart failure with preserved ejection fraction; HFr-EF: heart failure with reduce ejection fraction; IU/L: international units/liter; kg/m2: kilogram/square metre; LDL: Low-Density Lipoprotein; LVEF: left ventricular ejection fraction; mg/dL: milligram/deciliter;mmol/L: milimol/liter