Table 2.
Multiple regression analysis for prediction of epicardial adipose tissue UCP1, PGC1α and PRDM16 mRNA levels
| Variables | EAT UCP1 mRNA (R2=0.503) | EAT PGC1α mRNA (R2=0.641) | EAT PRDM16 mRNA (R2=0.499) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| β | 95%CI | P value | β | 95%CI | P value | β | 95%CI | P value | |
| Age | 0.071 | 0.019-0.132 | 0.032 | 0.099 | 0.032-0.199 | 0.003 | 0.079 | 0.041-0.177 | 0.041 |
| Gender (Man) | 0.119 | -0.043-(-0.291) | 0.040 | -0.152 | -0.064-(-0.237) | 0.001 | -0.101 | -0.041-(-0.301) | 0.041 |
| Body mass index | -0.090 | -0.002-(-0.301) | 0.041 | -0.181 | -0.001-(-0.248) | 0.039 | -0.088 | -0.012-(-0.431) | 0.049 |
| Obesity | -0.281 | -0.108-(-0.931) | 0.029 | -0.381 | -0.119-(-0.849) | 0.022 | -0.229 | -0.099-(-0.983) | 0.041 |
| Diabetes Mellitus | -0.230 | -0.101-(-0.931) | 0.041 | -0.460 | -0.159-(-0.869) | 0.044 | -0.201 | -0.032-(-0.899) | 0.044 |
| Hypertension | 0.083 | 0.021-0.333 | 0.044 | 0.131 | 0.021-0.343 | 0.039 | 0.072 | 0.012-0.435 | 0.049 |
| Dyslipidemia | 0.145 | -0.241-2.001 | 0.519 | 0.243 | -0.343-1.141 | 0.439 | 0.198 | -0.341-1.191 | 0.321 |
| Coronary artery Disease | -0.111 | -0.003-(-0.801) | 0.041 | -0.098 | -0.003-(-0.798) | 0.038 | -0.131 | -0.003-(-0.813) | 0.044 |
| LVEF | 0.222 | 0.081-0.344 | 0.002 | 0.399 | 0.049-0.598 | 0.001 | 0.119 | 0.052-0.301 | 0.002 |
Values were considered to be statistically significant when P < 0.05
CI: Confidence Interval; EAT: epicardial adipose tissue; LVEF: left ventricular ejection fraction; PGC1α: peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PRDM16: PR-domain-missing 16; UCP1: uncoupling protein 1.