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In one demonstration NanoScript-Sox9 was used to differentiate neural stem cells into functional neurons. Gene expression was determined for NanoScript compared to nanoparticles with just the DNA binding domain, or just the repressor peptide (c). Fluorescent microscopy is used to show TUJ1 staining (b). Calcium imaging was used to show functionality of the induced neurons (d,e). Adapted with permission from Wiley: Angewandte Chemie. (105) Copyright 2015
