Figure 2.
MHC-I expression increases after photothrombotic stroke. (A) Mouse ischemia 24 h after photothrombotic stroke. MRI-T2 imaging. (B) Expression of the MHC-I protein in the cerebral ischemic cortex from 3-24 h after ischemia in the photothrombotic model. (C) The changes in MHCⅠprotein expression between the left and right cerebral cortex were measured at different time points. (D) The changes in MHC-I protein expression in the cerebral cortex of the photothrombotic experimental group and the sham-operated group 6 h after ischemia. (E) Brain tissue immunofluorescence staining showing MHC-I expression in NeuN-positive neurons 24 h after photothrombotic ischemia (scale bar, 50 μm).