Figure 2.
Differential expression spectra between tumors and normal tissues across the 13 cancer types. (a) Expression boxplot of selected genes ranked by the CVAA. Each row in the first column indicates gene symbol, rank number and LOD value, respectively. Y axis of mRNA levels is log2 scaled. (b) Expression profile of the top 500 genes across the 13 cancer types. As tissue-varied gene expression, original expression values of each gene are percentile ranked (Methods) within each cancer type (color bar on the left top). (c) Multidimensional scaling shows relative similarity among all samples, with the circled dots indicating the normal tissues.