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. Author manuscript; available in PMC: 2017 Aug 18.
Published in final edited form as: JAMA Psychiatry. 2017 Apr 1;74(4):379–386. doi: 10.1001/jamapsychiatry.2017.0017

Figure 3. Corticothalamic Task-Based Functional Connectivity (tbFC) During Inhibitory Control (IC) Mediates the Association Between IC Task Accuracy and Smoking Outcomes.

Figure 3

A, In study 1 (cessation study), there was a significant indirect effect of IC task accuracy on smoking relapse outcomes via corticothalamic task-based functional connectivity (tbFC) such that increasing IC task accuracy and corticothalamic tbFC predicted maintaining abstinence (βi = −0.0078; bias-corrected and accelerated [BCa] 95%CI, −0.022 to −0.0002 [binary coding: abstinent, 0; relapsed,1]). B, In study 2 (laboratory study), the indirect effect of IC task accuracy via tbFC accounted for 51.7%of the total effect on time to smoke during the smoking relapse analog task (βi = 0.25; BCa 95%CI, 0.02 to 0.66). eTable 8 in the Supplement provides additional details.

aSignificant at P < .05.

bP = .07.