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. 2017 Aug 18;12(8):e0183178. doi: 10.1371/journal.pone.0183178

Fig 4. β-catenin activity mediates GLI2 activation in skin of YAP2-5SA-ΔC mice.

Fig 4

Immunofluorescence stainings of dorsal neck skin sections of P50 of YAP2-5SA-ΔC/K14-creERT/CtnnB1lox/lox and YAP2-5SA-ΔC/K14-creERT/CtnnB1-/- littermate mice detecting β-catenin (A, red), and GLI2 (C, green), and YAP (C, red). (B) Genotypic characterization of P50 YAP2-5SA-ΔC/K14-creERT/CtnnB1lox/lox and YAP2-5SA-ΔC/K14-creERT/CtnnB1-/- mutant littermate mice. Quantification of % GLI2 (D) and YAP (E) positive nuclei in the skin sections of P50 of YAP2-5SA-ΔC/K14-creERT/CtnnB1lox/lox and YAP2-5SA-ΔC/K14-creERT/CtnnB1-/- littermate mice. Basement membranes are demarcated with dashed lines. DAPI, 4, 6-diamidino-2-phenylindole. Scale bars = 20 μm.