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Percentage of PI-positive nuclei in thyroids of control and TH treated animals. Percentages of PI-positive nuclei in thyroids of T3-treated rats (7.1 ± 0.12, *p < 0.05) and T4-treated rats (9.1 ± 0.44, **p < 0.01) were significantly higher than in control animals (3.7 ± 0.53).