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. Author manuscript; available in PMC: 2017 Aug 18.
Published in final edited form as: J Pediatr. 2016 Nov 28;181:12–28.e1. doi: 10.1016/j.jpeds.2016.10.082

Table V.

Pharmacology of sBPD

Categories Medications Dosing Comments
Diuretics (Enteral dosing) Furosemide 1–2 mg/kg/dose q12–24h Often PRN
Chlorothiazide 20–40 mg/kg/d divided q12h
Spironolactone 2–4 mg/kg/d divided q12–24h
Bronchodilators Albuterol 2.5 mg nebulized or 2 puffs q4–12h Often PRN
Ipratropium 0.5 mg q6–12h Often PRN
Levalbuterol 0.31–1.25 mg or 2 puffs q4–12h Often PRN
Inhaled corticosteroids Beclomethasone 2 puffs q12h 40 or 80 mcg MDIs
Budesonide 1 neb q12–24h 0.25 or 0.5 mg nebs
Fluticasone 2 puffs q12h 44, 110, 220 mcg MDIs
Pulmonary hypertensive agents Bosentan ½ tab BID PO
Sildenafil 0.25–0.5 mg/kg/dose q 6–8 h
Treprostinil Starting dose: 2 ng/kg/min iv or SQ
Antireflux agents (enteral dosing) Erythromycin 2–4 mg/kg/dose q6–8h
Lansoprazole 0.5–1.0 mg/kg/dose BID
Metoclopramide 0.1–0.2 mg/kg/dose q6–8 h
Omeprazole 0.5–1.5 mg/kg/d
Ranitidine 2–4 mg/kg/d divided q8–12 h

MDI, metered dose inhaler; PRN, as needed.