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Fbx2 localizes to the somatodendritic region and to synaptic spines. Cultured hippocampal neurons were stained with antibodies as indicated. Green arrowheads show Fbx2 immunoreactivity in the spines. Red arrowheads show punctate staining juxtaposed to Fbx2 in the spines. Yellow arrowheads show colocalized puncta. Rectangles show the regions magnified. The enlarged image of Sec61β staining is the result of prolonged exposure to enhance details along the dendrite.
