Skip to main content
. Author manuscript; available in PMC: 2017 Aug 19.
Published in final edited form as: J Mol Biol. 2017 Feb 10;429(6):900–910. doi: 10.1016/j.jmb.2017.02.005

Fig. 4.

Fig. 4

Intermediates are part of the translocation pathway. Plot of fraction of events with subconductance state(s) (oscillating events), against voltage (mV), in (a) WT PA channel in the presence of L-Trp (black square), D-Trp (red circle), and D,L-Trp (blue triangle) peptides; and (b) PA R178A channel in the presence of L-Trp (black square), D-Trp (red circle), and D,L-Trp (blue triangle) peptides. (c) Plot showing the correlation of voltages obtained from midpoint of sigmoid plots from single-channel measurements, and voltages at which maximum binding occurs in ensemble measurements. Adjusted R2 value is 0.95.