Table 1.
Differentially regulated plasma proteins detected by proteomics.
| Protein | Protein coverage (%) | Number of peptides | Ratio KO/WT | SEM | P (ANOVA) |
|---|---|---|---|---|---|
| Coagulation factor XII | 28.3 | 29 | 0.96 | 0.0183 | 0.064 |
| Coagulation factor IX | 15.9 | 6 | 0.78 | 0.0521 | 0.003 |
| Coagulation factor X | 16.6 | 10 | 0.95 | 0.0428 | 0.403 |
| Prothrombin | 40.6 | 42 | 0.80 | 0.0169 | 0.000 |
| Coagulation factor V | 15.9 | 29 | 0.83 | 0.0236 | 0.000 |
| AntiThrombin-III | 51.8 | 55 | 0.94 | 0.0217 | 0.029 |
| Fibrinogen γ | 68.3 | 63 | 0.74 | 0.0189 | 0.000 |
| Fibrinogen β | 58.8 | 81 | 0.72 | 0.0167 | 0.000 |
| Coagulation factor XIIIa | 26.9 | 25 | 0.87 | 0.0260 | 0.001 |
| Coagulation factor XIIIb | 20.5 | 16 | 1.12 | 0.0433 | 0.023 |
| Fibronectin | 30.4 | 117 | 0.81 | 0.0119 | 0.000 |