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. 2017 Aug 18;7:8780. doi: 10.1038/s41598-017-09310-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Time gated visualization of ocular fundus pulsations. (a) The recorded volumes were time gated according to the heart cycle for visualization. The top row shows 3D renderings of the CS complex at four different IOP levels ranging from 15 mmHg to 95 mmHg at the instance of maximum deformation. The bottom row shows the corresponding volumes at half a heart cycle later. (b) Volumes are shown for motions exceeding 12 μm/s for the same datasets as shown in (a). Locally increased deformations were identified at higher IOP levels while the overall pulsatility decreased with increased IOP above 65 mmHg. (c,d) B-scans at the locations indicated by arrows in (b) are shown at IOPs of 65 mmHg and 95 mmHg, respectively. Regions undergoing increased deformations were identified around the ONH and larger choroidal vessels. (scale bar = 100 μm).