Table 1.
Measurement of the bacterial susceptibility to the AMP LL-37 was determined by using a modified version of the Calgary Biofilm Device (CBD) method59.
| Strain ID | Genotype ADSRRS-fingerprinting | Biofilm-Production OD600nm Mean (SD) | LL-37 (μΜ) | |
|---|---|---|---|---|
| MIC | MBEC | |||
| 13 | E | 0.89 (0.09) | 10 | >160 |
| 5 | N | 0.16 (0.04) | 20 | >160 |
| 3 | S | 0.20 (0.06) | 10 | >160 |
| 24 | L | 1.08 (0.11) | 20 | >160 |
| ATCC 29213 | NA | 0.42 (0.09) | 20 | >160 |
Minimum Inhibitory Concentration (MIC) and Minimal Biofilm Eradication Concentration (MBEC) are assessed among two low and two high biofilm producing isolates derived from skin of patients with AD, as well as the ATCC strain 29213.