Table 1.
Summary of demographics and disease severity of study subjects.
| AD | Healthy | Psoriasis | p-value | |
|---|---|---|---|---|
| Sample size | n = 59 | n = 18 | n = 22 | |
| Age (y) (mean, SD) | 40.5 (15.2) | 41.3 (10.3) | 46.8 (11.4) | 0.208 |
| BMI (mean, SD) | 27.7 (6.1) | 27.6 (4.4) | 31.5 (5.2) | *0.031 |
| SCORAD (mean, SD) | 54.1 (13.2) | NA | NA | |
| PASI (mean, SD) | NA | NA | 27.6 (9.9) | |
| Gender | *0.042 | |||
| Female (n, %) | 28 (47.5%) | 6 (33.3%) | 4 (18.2%) | |
| Male (n, %) | 31 (52.5%) | 12 (66.7%) | 18 (81.8%) | |
| Ethnicity | *** < 0.001 | |||
| Asian (n, %) | 15 (25.4%) | 3 (16.7%) | 2 (9.1%) | |
| African American (n, %) | 24 (40.7%) | 9 (50.0%) | 0 (0.0%) | |
| Caucasian (n, %) | 20 (33.9%) | 6 (33.3%) | 16 (72.7%) | |
| Serum IgE (kU/L) (median, IQR) | 2,412 (5,028) | NA | NA | NA |
| Eosinophils (%) (mean, SD) | 6.91 (4.94) | NA | NA | NA |
| Asthma bronchiale | ** < 0.001 | |||
| No | 39 (66.1%) | 18 (100.0%) | 21 (95.5%) | |
| Yes | 20 (33.9%) | 0 (0.0%) | 1 (4.5%) | |
| Arterial hypertension (AT) | 0.759 | |||
| No | 51 (86.4%) | 17 (94.4%) | 19 (86.4%) | |
| Yes | 8 (13.6%) | 1 (5.6%) | 3 (13.6%) | |
| Diabetes mellitus (DM) | 0.475 | |||
| No | 55 (93.2%) | 18 (100.0%) | 22 (100%) | |
| Yes | 4 (6.8%) | 0 (0.0%) | 0 (0.0%) | |
| Hypercholesterolemia (HCh) | 0.329 | |||
| No | 52 (88.1%) | 18 (100.0%) | 19 (86.4%) | |
| Yes | 7 (11.9%) | 0 (0.0%) | 3 (13.6%) | |
| Cardiovascular disease risk factor present (AT and/or DM and/or HCh) | 0.439 | |||
| No | 48 (81.4%) | 17 (94.4%) | 18 (81.8%) | |
| Yes | 11 (18.6%) | 1 (5.6%) | 4 (18.2%) |
One-way ANOVA was used for comparisons of means, and Fisher’s exact test was used for comparisons of proportions; *p < 0.05, **p < 0.01, ***p < 0.001; y years, SD standard deviation, IQR interquartile range.