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. 2017 Aug 18;7:8770. doi: 10.1038/s41598-017-09395-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of pretreatment with B. pseudocatenulatum LI09 or B. catenulatum LI10 on the alterations of gut bacterial taxonomic abundance during D-GalN-induced acute liver injury. (a) Bacterial taxa identified as differentially abundant between two groups analysed by linear discriminant analysis effect size (LEfSe). The bacterial taxa of the NC, LI09 and LI10 groups were compared with those of the PC group at different levels. Green indicates those bacterial taxa whose abundance were higher in the PC group, and red indicates those bacterial taxa whose abundance were higher in the other group. In addition, yellow indicates those bacterial taxa whose abundance show non-significant differences between the two groups. (b) The relative abundance at the bacterial family level in the LI09 or LI10 group was compared with that in the PC group. (c) The relative abundance at the bacterial genus level in the LI09 or LI10 group was compared with that in the PC group. Values are expressed as the median with interquartile range. *p < 0.05 compared with the PC group.