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. 2017 Aug 18;7:8770. doi: 10.1038/s41598-017-09395-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation-network analysis of plasma cytokines and gut bacterial genera of D-GalN-sensitized rats who received B. pseudocatenulatum LI09 or B. catenulatum LI10. A Spearman correlation analysis was performed, and only correlations with p < 0.05 are displayed. Blue nodes represent bacterial genera, and yellow nodes represent cytokines. The ellipses indicate that the depletion of the bacterial genera was alleviated compared to that in the PC group, and the round rectangles indicate that the enrichment of the bacterial genera was alleviated or the increase of the cytokines was alleviated compared to that in the PC group. A red line connecting nodes represents positive correlation, and a green line represents negative correlation. Values of the corresponding correlation coefficients are indicated by the thickness of the line; the thicker the line, the greater the coefficient.