Fig. 1.
Compound structures and syntheses in this study. (A and B) Chemical structures of aziridine and 2-ethyl-2-oxazoline, respectively. (C) Synthesis of fully deacylated linear PEI25 by exhaustive acid hydrolysis of its commercial predecessor. (D) Synthesis of fully deacylated linear PEI22, PEI87, and PEI217 by the acid hydrolysis of PEOZs. Conditions: (i) 24% (wt/vol) HCl, 110°C, 96 h; k = 517, l = 64, m = 581, PEI25; n = 504 for 50-kDa PEOZ, 2,018 for 200-kDa PEOZ, and 5,044 for 500-kDa PEOZ.