Table 4.

Multivariate Analysis

	Hazard ratio	95% CI	p Value
Gender	0.911	0.418-1.870	0.81
Smoking	0.596	0.263-1.293	0.19
Histology	0.274	0.147-0.501	<0.01
pT status	0.969	0.509-1.886	0.92
pN status	0.286	0.139-0.598	<0.01
TMI	0.429	0.241-0.752	<0.01

TMI, tumor marker index; CI, Confidence interval