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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Kidney Int. 2017 Mar 16;92(2):365–376. doi: 10.1016/j.kint.2017.01.020

Figure 7. Effect of high dose (HD) peritoneal dialysis (PD) on serum cytokines and lung inflammation in ischemic AKI, 4 hours after initiation of peritoneal dialysis.

Figure 7

Peritoneal dialysis (PD) or sham PD was performed one hour after sham operation (Sham) or ischemic AKI (AKI) for 4 hours with peritoneal dialysate exchanges occurring every 15 minutes [i.e., 4 exchanges per hour for four hours for a total of 16 exchanges]. Sham with no additional procedure (Sham + no PD) and AKI with no additional procedure (AKI + no PD) were also compared at the same time point. The following were determined 5 hours post Sham or AKI procedure: A) Serum IL-6, B) Serum CXCL1, C) Serum TNF, D) Serum IL-1β, E) Serum IFN-γ, F) Serum IL-10, G) Lung MPO activity, and H) Lung CXCL1. Comparisons were made using ANOVA with Tukey’s multiple comparison procedure. # NS versus AKI+no PD. Group numbers are Sham + No PD: n=5; Sham + Sham PD: n=5; Sham + High Dose PD: n=5; AKI + No PD : n=4; AKI + Sham PD: n=5; AKI + High dose PD: n=5.