Table 1.
Analysis of the Intrinsic Disorder Predisposition of Individual Human GRNs
| Name (length) | FoldIndexa | Mean PONDR disorder scoreb | |||
|---|---|---|---|---|---|
| NIDPR | Longest IDPR | NIDRes | % disorder | ||
| GRN‐1 (57) | 3 | 5 | 20 | 35.1 | 0.683 (0.593) |
| GRN‐2 (58) | 4 | 4 | 21 | 36.2 | 0.570 (0.564) |
| GRN‐3 (57) | 5 | 10 | 28 | 49.1 | 0.843 (0.778) |
| GRN‐4 (57) | 2 | 6 | 22 | 38.6 | 0.482 (0.416) |
| GRN‐5 (55) | 5 | 5 | 24 | 43.6 | 0.844 (0.733) |
| GRN‐6 (56) | 3 | 5 | 18 | 32.1 | 0.566 (0.538) |
| GRN‐7 (57) | 7 | 7 | 32 | 56.1 | 0.609 (0.560) |
| Mean GRN (55) | 4 | 4 | 24 | 43.6 | |
a
Table represents some of the disorder‐based characteristics of query proteins: “NIDPR” represents the number of intrinsically disordered protein regions (IDPRs) longer than 3 residues; “Longest IDPR” shows the length of the longest disordered region; “NIDRes” represents the number of predicted disordered residues; “% disorder” represents content of all disordered residues.
b
This column represents mean disorder score values generated by PONDR® VL3 and PONDR® for various human GRNs analyzed individually. Values in brackets show the region‐averaged disorder scores of GRNs within the PGRN sequence.