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IPF CD4 T cell proliferative responses to vimentin are HLA class II dependent. (A) Representative line graphs depicting that addition of F(ab′)2 anti-human HLA-DR (2 μg/ml) inhibits vimentin-induced (1 μg/ml) CD4 T cell proliferation. (B) Aggregate results of CFSE proliferation assays among Control (Con., n = 10) and IPF specimens (n = 15). *p < 0.05, **p < 0.01.
