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. Author manuscript; available in PMC: 2017 Aug 19.
Published in final edited form as: Vaccine. 2015 Oct 23;33(50):7051–7060. doi: 10.1016/j.vaccine.2015.09.112

Table 2.

DENV-2 strains commonly used in mouse models

Virus Description Reference
D2Y98P Singapore 1998. C6/36 mosquito cells p20 [59]
D2Y98P-PP1 Double plaque-purified clone of D2Y98P [61]
PL046 Taiwan, neurotropic [41]
D2S10 From PL046; ten alternate passages between C6/36 mosquito cells and AG129 mice i.v. [40]
S221 From D2S10; triple plaque-purified clone [44]
E124/128-IC PL046 infectious clone with mouse adapted mutations [42]
D220 From D2S10; ten alternate passages between C6/36 mosquito cells and AG129 mice s.c. [43]
D2S20 From D2S10; ten alternate passages between C6/36 mosquito cells and AG129 mice i.v. [45]