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. Author manuscript; available in PMC: 2018 Jan 26.
Published in final edited form as: J Med Chem. 2017 Jan 5;60(2):580–593. doi: 10.1021/acs.jmedchem.6b01148

Figure 6. Molecular mechanism of D3R partial activation.

Figure 6

Schematic representation shows the common trend of movements of TM helices and the extracellular loop regions based on the comparisons between the antagonist- and partial agonist-bound D3R MD simulations.